This depends on how you are planning to use the YubiKey.

For standard YubiKey functionality (Yubico OTP, OATH-HOTP, Challenge-Response, Static Password) over USB, YubiKeys use the same drivers as USB keyboards. If your device supports USB keyboards, it will work with the YubiKey. If your device does not load the driver, try plugging in a USB keyboard first.

For standard YubiKey functionality over NFC, the YubiKey NEO uses the NDEF4 standard. If your device supports this standard, it will work with the YubiKey.

For smart card functions, the YubiKey NEO uses the ISO 7816-4 standard over USB and the ISO 14443-4 standard over NFC. If your device supports these standards, it will work with the YubiKey.

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