Yes, the YubiKey can be used with any computer (including PCs) that have a standard USB 2.0 port and support USB keyboards. The YubiKey identifies itself to the computer as a USB Keyboard, and is therefore OS independent. It works with Microsoft Windows, Linux, Apple Mac OS X, Apple iOS (iPad/iPad 2/iPad 3 only). The YubiKey also works with Sony PS3, Microsoft Xbox360, Nintendo Wii, and so on, without requiring the installation of any device drivers, for OTP only.
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